[Native Antigen Company] New Omicron Antigens

Omicron Antigens

Native Antigen Company에서는 SARS-CoV-2 Omicron(B.1.1.529) variant에 대한 Whole Spike, S1 및 RBD Antigen을 제공합니다. 당사의 VirtuE 발현 시스템에서 생산된 Spike Antigen은 full glycosylation과 적절한 folding을 하고 있으므로 고품질의 immunoassay를 개발하고 특이적인 항체를 생성하는 데 이상적입니다.

Antigen Mutations in Reference to Wuhan-Hu-1 Wild-Type
Whole Spike
(REC32008)
A67V, Δ69-70, T95I, G142D, Δ143-145, Δ211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Spike S1
(REC32006)
A67V, Δ69-70, T95I, G142D, Δ143-145, Δ211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y
Spike RBD
(REC32007)
G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H

Our Antigens

The Native Antigen Company now offers three Spike antigens for the SARS-CoV-2 Omicron variant:

Whole Spike Antigen (REC32008)

Our trimeric whole Spike antigen is stabilised as a pre-fusion trimer via six amino acid (HexaPro) changes in the S2 subunit, in addition to a GSAS mutation in the furin cleavage site and a His-Strep-tag at the C-terminus for ease of purification.

Spike S1 Antigen (REC32006)

Our Spike S1 antigen includes residues 1-674 of the full Spike sequence and a C-terminal sheep Fc-tag for ease of purification.

Spike RBD Antigen

Our Spike receptor-binding domain (RBD) antigen includes residues 319-542 of the full Spike sequence and a C-terminal His-tag for ease of purification.

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