Omicron Antigens
Native Antigen Company에서는 SARS-CoV-2 Omicron(B.1.1.529) variant에 대한 Whole Spike, S1 및 RBD Antigen을 제공합니다. 당사의 VirtuE 발현 시스템에서 생산된 Spike Antigen은 full glycosylation과 적절한 folding을 하고 있으므로 고품질의 immunoassay를 개발하고 특이적인 항체를 생성하는 데 이상적입니다.
| Antigen | Mutations in Reference to Wuhan-Hu-1 Wild-Type |
| Whole Spike (REC32008) |
A67V, Δ69-70, T95I, G142D, Δ143-145, Δ211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F |
| Spike S1 (REC32006) |
A67V, Δ69-70, T95I, G142D, Δ143-145, Δ211, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y |
| Spike RBD (REC32007) |
G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H |
Our Antigens
The Native Antigen Company now offers three Spike antigens for the SARS-CoV-2 Omicron variant:
Whole Spike Antigen (REC32008)
Our trimeric whole Spike antigen is stabilised as a pre-fusion trimer via six amino acid (HexaPro) changes in the S2 subunit, in addition to a GSAS mutation in the furin cleavage site and a His-Strep-tag at the C-terminus for ease of purification.
Spike S1 Antigen (REC32006)
Our Spike S1 antigen includes residues 1-674 of the full Spike sequence and a C-terminal sheep Fc-tag for ease of purification.
Spike RBD Antigen
Our Spike receptor-binding domain (RBD) antigen includes residues 319-542 of the full Spike sequence and a C-terminal His-tag for ease of purification.
