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SignalChem Diagnostics - Provides Raw Materials for In-vitro diagnostic (IVD) tests

Proteins, enzymes and compounds suitable for the development of IVDs

CRISPR 기반의 진단 제품들은 코로나19 팬데믹 기간 동안 clinical laboratory testing solutions에 진출하는 등 예상치 못한 생화학적 현상에서 분자 진단을 위한 강력한 플랫폼으로 5년도 채 되지 않아 진화했습니다.
SignalChem Diagnostics는 gene-editing application 분야의 요구에 맞춘 highly active CRISPR enzymes을 제공합니다. Our selection of CRISPR enzymes ensures exceptional specificity, efficiency, and versatility in various CRISPR-based gene manipulation techniques, enabling the development of innovative and reliable gene-editing solutions.

제품명을 클릭하면 자세한 정보를 확인하실 수 있습니다.

Name Catalog # Source Organism Expression Host Organism Tag Type Sequence
AapCas12b, Active C12B1-E311U Alicyclobacillus acidiphilus E.coli Tag-free full length
AsCas12a, Active CS12A-E311H Acidaminococcus sp E.coli His full length
Cas12 (LbCpf1), Active C12CR-E241G Lachnospiraceae E.coli GST full-length
EiCsm6, Active CS06-E312H Enterococcus italicus E.coli His full length
LbuCas13a, Active CS13A-E322U Leptotrichia buccalis E.coli Tag-free full length
LbuCas13a, Active, Glycerol-free CS13A-E322UB Leptotrichia buccalis E.coli Tag-free full-length
LwCas13a, Active CS13A-E321H Leptotrichia wadei E.coli His full length
PsmCas13b, Active CS13B-E312H Prevotella sp E.coli His full length
SpCas9 (D10A)-NLS CS09N-E331H Streptococcus pyogenes E.coli His full length
SpCas9 (D10A, H840A)-NLS CS09N-E333H Streptococcus pyogenes E.coli His full length
SpCas9 (H840A)-NLS CS09N-E332H Streptococcus pyogenes E.coli His full length
SpCas9, Active CS09-E311H Streptococcus pyogenes E.coli His full length
SpCas9-NLS, Active CS09N-E312H Streptococcus pyogenes E.coli His full length
SpCas9-NLS, Glycerol-free CS09N-E312HB Streptococcus pyogenes E.coli His full length
TccCas13a, Active CS13A-E314H Thermoclostridium caenicola E.coli His full length
TtCsm6, Active CS06-E311H Thermus thermophilus E.coli His full length

AsCas12a, Active (# CS12A-E311H)

AsCas12a is a Cas endonuclease from Acidaminococcus sp. Engineered AsCas12a systems can be used for accurate editing in hematopoietic stem cells, induced pluripotent stem (iPS) cells, and natural killer (NK) cells. AsCas12a nuclease activity assayed using a fluorogenic substrate and 10nM of enzyme as per the Cas12 Activity Assay Protocol provided below.

LwCas13a, Active (# CS13A-E321H)

Cas13a is an RNA-guided RNA endonuclease that belongs to the class 2 type VI CRISPR-Cas system. LwaCas13a collateral RNA cleavage activity assayed using a fluorogenic substrate and 100nM of enzyme as per the Cas13 Activity Assay Protocol provided below. RNP = Cas13-sgRNA ribonucleoprotein complex. TR = target ssRNA.

Plant Expression Systems의 사용은 allergen production에 대한 혁신적이고 효율적인 접근법을 제공함으로써 allergy detection에 혁신을 일으키고 있습니다. Plant Expression Systems의 힘을 활용함으로써 연구자들은 allergen을 효과적으로 연구할 수 있으며, allergy 연구를 발전시키고, diagnostics을 개선할 수 있습니다. Plant Expression Systems을 이용한 allergy detection의 매력적인 세계로 뛰어들어 이 기술이 allergy 연구와 진단의 미래를 어떻게 형성하고 있는지 SignalChem Diagnostics과 함께 시작해 볼까요?

Plant Expression Systems의 장점

  • High-Level Allergen Production

  • Proper Protein Folding and Post-Translational Modifications
    Allergen Products는 정확한 Protein Folding 및 정밀한 Post-Translational Modification을 보장하며, 이것은 allergen의 구조적, 기능적, 생물학적 특성에 필수적입니다. 이러한 특성들은 정확한 allergy detection과 allergen-host interactions 이해에 중요합니다. 

  • Safety and Scalability
    Plant Expression Systems은 bacteria, yeast 및 mammalian cell cultures와 같은 기존의 발현 시스템에 비해 human pathogens으로부터의 감염 위험을 최소화하여 더 안전한 대안을 제공합니다. 게다가, 생산 과정은 쉽게 확장 가능하여 다양한 연구 needs를 충족시킬 수 있고, 모든 규모의 프로젝트에 효율적인 allergen 생산이 가능합니다.

  • Innovative Research Opportunities
    Plant Expression Systems
    의 사용은 allergy 연구의 새로운 가능성을 열어, allergen structures, host response 및 novel diagnostics methods 연구를 포함합니다. 이러한 발전은 궁극적으로 allergy에 대한 이해를 높이고 보다 효과적인 치료법 개발에 기여합니다.

  • Potential for Personalized Medicine
    Plant Expression Systems은 개인 맞춤형 allergy diagnostics & treatments 개발할 수 있는 가능성을 제공합니다. Allergen 제품을 환자 개개인의 필요에 맞게 맞춤화함으로써, 임상의는 진단 정확성을 높이고 보다 효과적인 알레르기 관리를 위한 맞춤형 치료 계획을 만들 수 있을 수 있습니다.

제품명을 클릭하면 자세한 정보를 확인하실 수 있습니다.

Name Catalog # Source Organism Expression Host
Tag Type Genbank Accession
Alt a 1 AL01-A931H Alternaria alternata E.coli His AY117038.1
Art v 1 AV01-A921H Artemisia vulgaris Tobacco His AF493943.1
Art v 3 AV03-A921H Artemisia vulgaris Tobacco His EU564845.1
Art v 3.02 AV02-A921H Artemisia vulgaris E.coli His EU564845.1
Asp f 3 AF03-A931H Aspergillus fumigatus E.coli His U58050.1
Asp f 5 AF05-A931H Aspergillus fumigatus E.coli His Z30424.1
Asp f 6 AF06-A931H Aspergillus fumigatus E.coli His U53561.1
Asp f 9 AF09-A931H Aspergillus fumigatus E.coli His AJ223327.1
Can f 1 CF01-A951H Canis familiaris E.coli His AF027177.1
Can f 2 CF02-A951H Canis familiaris E.coli His AF027178.1
Can f 3 CF03-A951H Canis familiaris E.coli His AB090854.1
Can f 5 CF05-A951H Canis familiaris E.coli His Y00751
Cra c 8 CC08-A951H Crangon crangon E.coli His FJ462738.1
Der f 1 DF01-A941H Dermatophagoides farinae E.coli His AB034946.1
Der f 2 DF02-A941H Dermatophagoides farinae E.coli His D10447.1
Der p 2 DP02-A941H Dermatophagoides pteronyssinus E.coli His AF276239.1
Der p 21 DP21-A941H Dermatophagoides pteronyssinus E.coli His DQ354124.1
Der p 21/23 DP22-A941H Dermatophagoides pteronyssinus E.coli His Der p 21: DQ354124.1
Der p 23: EU414751.1
Der p 23 DP23-A941H Dermatophagoides pteronyssinus E.coli His EU414751.1
Der p 7 DP07-A941H Dermatophagoides pteronyssinus E.coli His U37044.1
Fel d 1 FD01-A951H Felis catus E.coli His chain 1: NM_001048153.1
chain 2: NM_00104.1
Fel d 4 FD04-A951H Felis catus E.coli His NM_001009233.1
Gly m 3 GM03-A921H Glycine max Tobacco His AJ223982.1
Lit v 2 LV02-A951H Litopenaeus vannamei E.coli His DQ975203.1
Lit v 3 LV03-A951H Litopenaeus vannamei E.coli His EU449515.1
Lit v 4 LV04-A951H Litopenaeus vannamei E.coli His FJ184279.1
Man i 3 MN03-A921H Mangifera indica Tobacco His DQ270547.1
Pen ch 18 PC18-A961H Penicillium chrysogenum E.coli His AF264027.1
Pis v 2 PV02-A921H Pistacia vera Tobacco His DQ631676.1

SignalChem Diagnostics offers a unique range of immunodiagnostics products, including antibodies, allergens, affinity proteins, and antigens. These products are carefully designed for a variety of immunodiagnostic assays. Our exceptional offerings are engineered to provide unmatched precision and sensitivity. They are optimized to suit a wide range of applications, ensuring consistent and reliable performance in techniques like ELISA, Western blot, immunoprecipitation, and other immunoassay methods.


CRISPR-Associated Products

gRNA Design Tool

immunodiagnostic product

Immuno Diagnostic Products

Kits for Animal Health


Clinical Chemistry


molecular diagnostic product

Molecular Diagnostic-Related Products

Enzymes (cDNA 합성, PCR & qPCR reagents)
Reagents (dNTP)
Isothermal Amplification


COVID-19 Related Products

Cell lines
Assay Kits


General Reagents

Affinity Proteins & Resins (Protein A/G/L)

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