[ATCC] Coronavirus Research Materials (2022.03 신제품 오미크론 변이 바이러스+ Antibodies 추가)

Corona-flyer-V3-Head-01

Credible solutions for critical public health emergencies
The outbreak of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has put the health and safety of the global community at risk. With the virus continuing to spread and the number of confirmed cases and deaths rising, the World Health Organization has declared the outbreak a public health emergency of international concern. As in previous public health emergencies such as Zika, SARS, MERS, and the H1N1 2009 pandemic, ATCC stands ready to partner with the dedicated scientists working toward preventing and containing this devastating outbreak.

HISARS-Cov2
HISARS-Cov2

Synthetic Molecular Standards for SARS-CoV-2
The pathogenic nature and transmission dynamics of SARS-CoV-2 has necessitated that the utmost care should be taken when handling the virus. To help ensure the safety of laboratory researchers, ATCC has developed four quantitative synthetic molecular standards for use as controls in the development of assays designed to detect and quantify SARS-CoV-2. Because these standards are synthetically derived, they eliminate the need to culture viruses in the laboratory and they are safe to use under biosafety level 1 conditions. Further, SARS-CoV-2 construct 1 is compatible with the nucleocapsid-targeted real-time RT-PCR primer and probe sets developed by the CDC.

sars-coV_synthetic
ATCC® No.  Description Compatible assays
VR-3276SD™ Quantitative Synthetic SARS-CoV-2 RNA containing portions of ORF1ab, N, E, nsp12 (RdRp), and ORF1b-nsp14 genes

China CDC Primers and probes for detection 2019-nCoV (24 January 2020)

Diagnostic detection of Wuhan coronavirus 2019 by real-time RT-PCR – Charité, Berlin Germany (17 January 2020)

Detection of 2019 novel coronavirus (2019-nCoV) in suspected human cases by RT-PCR – Hong Kong University (23 January 2020)

PCR and sequencing protocol for 2019-nCoV – Department of Medical Sciences, Ministry of Public Health, Thailand (Updated 28 January 2020)

US CDC Real-Time RT-PCR Panel for Detection 2019-Novel Coronavirus (28 January 2020)

US CDC panel primer and probes– U.S. CDC, USA (28 January 2020)

VR-3277SD™ Quantitative Synthetic SARS-CoV-2 RNA: containing a portion of Spike 5’ end gene. Detection of WN-Human1 sequence from clinical specimen. – National Institute of Infectious Diseases Japan (17 January 2020)
VR-3278SD™ Quantitative Synthetic SARS-CoV-2 RNA: containing a portion of Spike 3’ end gene. PCR and sequencing protocols for 2019-nCoV- National Institute of Infectious Diseases Japan (24 January 2020)
VR-3279SD™ Quantitative Synthetic SARS-CoV-2 RNA containing the portion of nsp9 and nsp12 (RdRp) genes RT-PCR assays for the detection of SARS-CoV-2 with RdRp – Institut Pasteur, Paris (2 March 2020)
Diagnostic detection of Wuhan coronavirus 2019 by real-time RT-PCR – Charité, Berlin Germany (17 January 2020)

Coronavirus Research Materials
Having access to a variety of coronavirus strains is essential for establishing the inclusivity and exclusivity of a novel assay. To support this need, ATCC provides viral strains and nucleic acids representing alpha coronaviruses and beta coronaviruses known to cause disease in humans. Explore our complete collection of research materials at www.atcc.org/coronavirus.

 

ATCC® No. Product Description
Viral strains  
VR-1986HK™ Heat-inactivated 2019 Novel coronavirus strain 2019-nCoV/USA-WA1/2020
VR-3326HK™ Heat-inactivated SARS-CoV-2 variant B.1.1.7
VR-3327HK™ Heat-inactivated SARS-CoV-2 variant B.1.351
VR-3342HK™ Heat-inactivated SARS-CoV-2 Delta variant
VR-3347HK™ Heat-inactivated SARS-CoV-2 Omicron variant (NEW)
VR-1558™ Betacoronavirus 1 strain OC43
VR-740™ Human coronavirus 229E
Genomic RNA  
VR-1992D™ Genomic RNA from SARS-CoV-2 strain 2019-nCoV/Italy/INMI1
VR-1986D™ Genomic RNA from SARS-CoV-2 strain 2019-nCoV/USA-WA1/2020
VR-1994D™ Genomic RNA from SARS-CoV-2 strain Germany/BavPat1/2020
VR-1991D™ Genomic RNA from SARS-CoV-2 strain Hong Kong/VM20001061/2020
VR-3326D™ Genomic RNA from SARS-CoV-2 strain USA/CA_CDC_5574/2020 (variant B.1.1.7)
VR-3327D™ Genomic RNA from SARS-CoV-2 strain USA/MD-HP01542/2021  (variant B.1.351)
VR-3342D™ Quantitative genomic RNA from SARS-CoV-2 strain USA/MD-HP05285/2021 (Delta variant)
VR-3347D™ Quantitative genomic RNA from SARS-CoV-2 strain USA/GA-EHC-2811C/2021 (Omicron variant) (NEW)
VR-1558DQ™ Quantitative Genomic RNA from Betacoronavirus 1 OC43
VR-740DQ™ Quantitative Genomic RNA from Human coronavirus 229E
VR-1558D™ RNA from Betacoronavirus 1 OC43
VR-740D™ RNA from Human coronavirus 229E
Synthetic RNA  
VR-3262SD™ Quantitative Synthetic Human coronavirus HKU1 RNA
VR-3263SD™ Quantitative Synthetic Human coronavirus NL63 RNA
VR-3248SD™ Quantitative Synthetic Middle East respiratory syndrome coronavirus (MERS-CoV) RNA
VR-3280SD™ Quantitative Synthetic SARS-CoV [2003] RNA
VR-3278SD™ Quantitative Synthetic SARS-CoV-2 RNA (3’ portion of S gene)
VR-3277SD™ Quantitative Synthetic SARS-CoV-2 RNA (5’ portion of S gene)
VR-3279SD™ Quantitative Synthetic SARS-CoV-2 RNA (nsp9, nsp12 [RdRp])
VR-3276SD™ Quantitative Synthetic SARS-CoV-2 RNA (portions of ORF 1ab, E, N genes)
ATCC® No. Product Description
VR-1997™ Polyclonal Anti-SARS-CoV-2 Spike Glycoprotein
VR-3328™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP1B3
VR-3329™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP1B11
VR-3330™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP1C3
VR-3331™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP1D10
VR-3332™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP1E6
VR-3333™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP1F2
VR-3334™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP2C2
VR-3335™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP2C7
VR-3336™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP2E7
VR-3337™ Monoclonal Anti-SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain, Clone 2TP2F2

Cell Lines for SARS-CoV-2 Propagation
To develop new vaccines or test antiviral compounds, researchers need access to virus isolates. However, during the outbreak of a novel virus like SARS-CoV-2, it can be challenging to determine which propagation host is ideal for successful viral replication. In a recent study by Harcourt J, et al., it was discovered that SARS-CoV-2 can replicate to a high titer in Vero CCL-81 and Vero E6 cells in the absence of trypsin. These cell lines and the media needed to cultivate them are available at ATCC—explore our collection today.

ATCC® No. Product Description
HTB-37™ Caco-2 [Caco2]
HTB-55™ Calu-3
CCL-244™ HCT-8
CCL-171™ MRC-5
CCL-81™ Vero
CRL-1586™ Vero C1008 [Vero 76, clone E6, Vero E6]
CCL-81-VHG™ Vero.STAT1 KO
Host_cell_SARS-Cov2

COR-122021-v15
©2021 American Type Culture Collection. The ATCC trademark and trade name, and any other trademarks listed in this publication are trademarks owned by the American Type Culture Collection unless indicated otherwise. ddPCR is a trademark of Bio-Rad Laboratories, Inc. IRDye® is a registered trademark of LI-COR Biosciences. MagicMark™ XP is a trademark of Thermo Fisher Scientific. These products are for laboratory use only. Not for human or diagnostic use. ATCC products may not be resold, modified for resale, used to provide commercial services or to manufacture commercial products without prior ATCC written approval.

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