행사 기간: 2023년 2월 6일 ~ 4월 24일까지
• 행사 대상: Full-size (150 μL) Unconjugated Monoclonal Primary Antibody
• 행사 제외 대상: Proteintech 홈페이지 할인 행사와 중복 적용 불가
• Low background, high specificity
• KD/KO validated (품목 지속적으로 확대 중)
Monoclonal antibodies: Advantages and disadvantages
Advantages:
-
Batch-to-batch reproducibility (high homogeneity).
-
Possibility to produce large quantities of identical antibody (an advantage for diagnostic manufacturing and therapeutic drug development).
-
High specificity to a single epitope reflected in low cross-reactivity.
-
More sensitive in assays requiring quantification of the protein levels.
-
Low background noise.
Disadvantages:
-
More expensive to produce. It is necessary to produce a pool of several monoclonal antibodies.
-
Requires significantly more time to produce and develop the hybridized clone (+/- 6 months).
-
More susceptible to binding changes when labeled (e.g. with a chromogen or a fluorophore).
Polyclonal antibodies: Advantages and disadvantages
Advantages:
-
Inexpensive and relatively quick to produce (+/- 3 months).
-
Higher overall antibody affinity against the antigen due to the recognition of multiple epitopes.
-
Have a high sensitivity for detecting low-quantity proteins.
-
High ability to capture the target protein (recommended as the capture antibody in a sandwich ELISA).
-
Antibody affinity results in quicker binding to the target antigen (recommended for assays that require quick capture of the protein; e.g., IP or ChIP).
-
Superior for use in detecting a native protein.
-
Easy to couple with antibody labels and rather unlikely to affect binding capability.
Disadvantages:
-
Batch-to-batch variability as produced in different animals at different times.
-
High chance of cross-reactivity due to a recognition of multiple epitopes (affinity purified antibodies display a minimum cross-reactivity).
제품 정보는 Proteintech 홈페이지(https://www.ptglab.com)에서 확인 가능합니다.
행사 적용 여부는 지사/대리점으로 문의 부탁드립니다.
* 주문 및 견적 문의는 지사/대리점으로 연락 주세요.
- 지사/대리점 안내Opens in a new tab
